黄建安

（1）研究方向

1.肺部肿瘤的临床与基础研究

2.急性肺损伤

（2）招生专业

临床医学-内科学-呼吸系病学

（3）招生类型

学术型博士、专业型/临床型博士、学术型硕士、专业型硕士

（4）E-mail

huang_jian_an@163.com

（5）导师简介

黄建安，中共党员、医学博士、主任医师、二级教授、博士生导师，现任苏州大学附属第一医院内科主任、呼吸与危重症医学科主任和苏州大学呼吸疾病研究所所长。享受国务院政府特殊津贴，是国家卫生健康委医疗应急工作专家组呼吸内科组成员、江苏省有突出贡献中青年专家。从医40载，他瞄准学科发展方向，领导团队先后获国家呼吸系统疑难病症诊治能力提升工程（全国仅10家）、国家临床重点专科、省医学重点学科；聚焦专科前沿技术，研究成果发表在JCI、CHEST等著名杂志，获省部级奖5项（含江苏省科学技术一等奖1项）；引领行业高质量发展，制定专业领域诊疗指南、共识18项；荣获全国五一劳动奖章、江苏省优秀共产党员、江苏省抗击新冠肺炎疫情先进个人等多项荣誉称号。现任江苏省医学会呼吸病学分会前任主任委员、江苏省预防医学会呼吸系统疾病预防与控制专业委员会主任委员、江苏省医师协会呼吸医师分会会长、江苏省呼吸内科质控中心主任、中国医师协会呼吸医师分会常务委员，获第八届中国呼吸医师奖。

（6）代表性论文

1.Gao L, Wang A, Chen Y, Cai X, Li Y, Zhao J, Zhang Y, Zhang W, Zhu J, Zeng Y, Liu Z, Huang JA.FTO facilitates cancer metastasis by modifying the m6A level of FAP to induce integrin/FAK signaling in non-small cell lung cancer. Cell Commun Signal. 2023 Nov 2;21(1):311.

2. Gong WT, Zhao XJ, Wang GM, Ma XL, Huang JA. Efficacy of Zidovudine-Amikacin Combination Therapy In Vitro and in a Rat Tissue Cage Infection Model against Amikacin-Resistant, Multidrug-Resistant Enterobacteriales.Microbiol Spectr. 2023 Mar 22;11(2):e0484322. 

3. Shen D, Zeng Y, Zhang W, Li Y, Zhu J, Liu Z, Yan Z, Huang JA. Chenodeoxycholic acid inhibits lung adenocarcinoma progression via the integrin α5β1/FAK/p53 signaling pathway.Eur J Pharmacol. 2022 May 15;923:174925.

4. Zou J, Li L, Zheng P, Liang W, Hu S, Zhou S, Wang Y, Zhao J, Yuan D, Liu L, Wu D, Xu M, Zhang F, Zhu M, Wu Z, Cao X, Ni M, Ling X, Wu Y, Kuang Z, Hu M, Li J, Li X, Guo X, Xu T, Jiang H, Gao C, Yu M, Liu J, Zhong N, Zhou J, Huang JA, Jin T, He J. Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.J Clin Invest. 2022 Feb 15;132(4):e154987.

5. Wang A, Yang W, Li Y, Zhang Y, Zhou J, Zhang R, Zhang W, Zhu J, Zeng Y, Liu Z, Huang JA. CPNE1 promotes non-small cell lung cancer progression by interacting with RACK1 via the MET signaling pathway.Cell Commun Signal. 2022 Jan 31;20(1):16. 

6. Zhang R, Zhang W, Zeng Y, Li Y, Zhou J, Zhang Y, Wang A, Lv Y, Zhu J, Liu Z, Huang JA. The regulation of CPNE1 ubiquitination by the NEDD4L is involved in the pathogenesis of non-small cell lung cancer.Cell Death Discov. 2021 Nov 6;7(1):336.

7. Shi CL, Zhang JP, Xu P, Li J, Shen J, Wu MY, Ye ZJ, Yu X, Song HF, Chen H, Xu JC, Pang Y, Huang JA. Upregulation of PD-1 expression on circulating CD8+ but not CD4+ T cells is associated with tuberculosis infection in health care workers. BMC Immunol. 2021 Jun 25;22(1):39.

8. Fu Y, Zhang Y, Lei Z, Liu T, Cai T, Wang A, Du W, Zeng Y, Zhu J, Liu Z, Huang JA. Abnormally activated OPN/integrin αVβ3/FAK signalling is responsible for EGFR-TKI resistance in EGFR mutant non-small-cell lung cancer. J Hematol Oncol. 2020 Dec 7;13(1):169. 

9. Wang Y, Zhong W, Salam A, Tarning J, Zhan Q, Huang JA, et al. Phase 2a, open-label, dose-escalating, multi-center pharmacokinetic study of favipiravir (T-705) in combination with oseltamivir in patients with severe influenza. EBioMedicine. 2020 Dec;62:103125. 

10. Du W, Zhu J, Zeng Y, Liu T, Zhang Y, Cai T, Fu Y, Zhang W, Zhang R, Liu Z, Huang JA. KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway. Cell Death Differ. 2021 Apr;28(4):1284-1300.